A CONDITIONAL ENTROPY BASED FEATURE SELECTION FOR SOFT SENSOR DEVELOPMENT IN CHEMICAL PROCESSES



In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo

In vitro differentiation of human induced pluripotent stem cells (iPSCs) into beta cells represents an important cell source for diabetes research.Here, we fully characterized iPSC-derived beta cell function in vitro and in vivo in humanized mice.Using a 7-stage protocol, human iPSCs were differentiated into islet-like aggregates with a yield of in

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Evaluation of toxicity, local biocompatibility, biodegradation, and systemic metabolism of cellulose/alginate/strontium apatite membranes implanted subcutaneously in mice

ABSTRACT Purpose: To evaluate membranes originating from pure or oxidized blade eraser bacterial cellulose (BC)/alginate/strontium apatite hydrogels regarding toxicity, biocompatibility, biodegradation and metabolism.Methods: The toxicity was measured by incubating the materials with Artemia salina for 24 h, and mortality and the 50% lethal concent

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